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Mechanistically, the binding of BPC157 to FBXO22 induces steric hindrance that suppresses FBXO22-mediated ubiquitination and degradation of its substrate BACH1

Nutritional biochemistry

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Khavinson VKh, Yuzhakov VV, Kvetnoi IM, Malinin VV, Popuchiev VV, Fomina NK

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While robust human clinical trials are still underway, preclinical studies and patient stories suggest several promising mechanisms: BPC-157 promotes angiogenesis, or the formation of new blood vessels